- As a first synthetic antineoplastic anthracenedione
agent, Novantrone inhibits both RNA and DNA synthesis
of cancer cell to be associated with the inhibition of
nucleic acid synthesis, resulting in cell death.
- Novantrone, a consistent finding in clinical studies
in various neoplasms has been a lower frequency and usually
lesser intensity of acute side effects coming out from
traditional anthracyclines such as cardiotoxicity and
nausea, vomiting, alopecia, and stomatitis
Acute Myeloblastic Leukemia(AML) & Acute
Lymphoblastic Leukemia(ALL), Advanced Breast Cancer(ABC),
Non-Hodgkin's Lymphoma(NHL), Prostate Cancer
